~ Cervical Cancer ~
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Physical Examination* |
Palpable lymph nodded Examine vagina Bimanual rectovaginal examination (under anesthesia) |
Radiologic Studies* |
IVP Barium enema CxR Skeletal X-ray |
Procedures* |
Biopsy Conization Colposcopy Endocervical curettage Cystoscopy Proctoscopy |
Optional Studies¡K |
Computerized axial tomography Lymphangiography Ultrasonography Magnetic resonance imaging Radionucleotide scanning Laparoscopy |
* Allowed by the International Federation of gynecology and Obstetrics (FIGO)
¡K Information that is not allowed by FIGO to change the clinical stage
ø Colposcopy of the invasive lesions:
1). Abnormal blood vessels:
- Looped vessels
: most common arising from the punctation and mosaic vessels present in cervical intraepithelial neoplasia (CIN)- Branching vessels
: arising from the cervical stroma- Reticular vessels
: the terminal capillaries of the cervical epithelium
2). Irregular surface contour:
- As a result of epithelium ulceration or papillary characteristic of the lesion
3). Color tone change:
- Attributed to increasing vascularity, surface epithelial necrosis, and production of keratin
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Stage 0 |
Carcinoma in situ, intraepithelial carcinoma |
Stage I |
The carcinoma is strictly confined to the cervix (extension to the corpus should be disregarded) |
Stage Ia |
Invasive cancer identified only microscopically; all gross lesions even the superficial invasion are stage Ib cancers. Invasion is limited to measured stromal invasion with maximum depth of 5.0 mm and no wider than 7.0 mm |
Stage Ia1 |
Measured invasion of stroma no greater than 3.0 mm in depth and no wider than 7.0 mm. |
Stage Ia2 |
Measured invasion of stroma greater than 3 mm and no greater than 5 mm and no wider than 7 mm. The depth of invasion should not be more than 5 mm taken from the base of the epithelium, surface or glandular, from which it originates. Vascular space involvement, venous or lymphatic, should not alter the staging. |
Stage Ib |
Clinical lesion confined to the cervix or preclinical lesion greater than stage Ia. |
Stage Ib1 |
Clinical lesions no greaten than 4.0 cm in size |
Stage Ib2 |
Clinical lesions greater than 4 cm in size |
Stage II |
Involvement of the vagina but not the lower third, or infiltration of the parametria but not out to the sidewall. |
Stage IIa |
Involvement of the vagina but no evidence of parametrial involvement |
Stage IIb |
Infiltration of the parametria but not out to the sidewall |
Stage III |
Involvement of the lower third of the vagina or extension to the pelvic sidewall; all cases with a hydronephrosis or nonfunctioning kidney should be included, unless they are know to be attributable to other cause |
Stage IIIa |
Involvement of the lower third of the vagina but not out to the pelvic sidewall if the parametria are involved |
Stage IIIb |
Extension onto the pelvic sidewall and/or hydronephrosis or nonfunctional kidney |
Stage IV |
Extension outside the reproductive tract |
Stage IVa |
Involvement of the mucosa of the bladder or rectum |
Stage IVb |
Distant metastasis or disease outside the true pelvis |
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s Surgical Therapy:
¹
Stage Ia1: lesions with invasion less then 3 mm in depth (o )
- If no lymph vascular space invasion:
j extrafascial hysterectomy without node dissection
k Therapeutic conization (for those patients desiring childbearing capability)
- If positive lymph vascular space invasion:
j extrafascial hysterectomy with pelvic node dissection, or
k modified radical hysterectomy with pelvic node dissection
¹ Stage Ia2: lesions with invasion between 3-5 mm in depth (o )
¡V Modified radical hysterectomy with pelvic node dissection
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Stage Ib/IIa:¡V Radical hysterectomy, pelvic lymphadenectomy, and para-aortic lymph node evaluation
ø Types of Hysterectomy:
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Type I |
Extrafascial Hysterectomy |
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Type II |
Modified Radical Hysterectomy |
Medial 1/2 of the cardinal ligament and uterosacral ligament |
Type III |
Radical Hysterectomy |
Most of the cardinal ligaments and uterosacral ligament Upper 1/3 of the vagina |
Type IV |
Extended Radical Hysterectomy |
Most of the cardinal ligaments and uterosacral ligament Up to 3/4 of the vagina Periureteral tissue Superior vesicle artery |
Type V |
Partial Exenteration |
Most of the cardinal ligaments and uterosacral ligament Up to 3/4 of the vagina Portions of the distal ureter and bladder |
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s Radiation Therapy:
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Filename: Cervical Cancer
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