¦V¤W Intraepithelial disease Cancer Staging Endometrial Ca Endometrial Hyperplasia Cervical Ca

~ Cervical Cancer ~

¡@

  1. Staging Procedures:

Physical Examination*

Palpable lymph nodded

Examine vagina

Bimanual rectovaginal examination (under anesthesia)

Radiologic Studies*

IVP

Barium enema

CxR

Skeletal X-ray

Procedures*

Biopsy

Conization

Colposcopy

Endocervical curettage

Cystoscopy

Proctoscopy

Optional Studies¡K

Computerized axial tomography

Lymphangiography

Ultrasonography

Magnetic resonance imaging

Radionucleotide scanning

Laparoscopy

* Allowed by the International Federation of gynecology and Obstetrics (FIGO)

¡K Information that is not allowed by FIGO to change the clinical stage

ø Colposcopy of the invasive lesions:

1). Abnormal blood vessels:

2). Irregular surface contour:

3). Color tone change:

¡@

  1. FIGO Staging of Cervical Carcinoma:
  2. ¡@

    Stage 0

    Carcinoma in situ, intraepithelial carcinoma

    Stage I

    The carcinoma is strictly confined to the cervix (extension to the corpus should be disregarded)

    Stage Ia

    Invasive cancer identified only microscopically; all gross lesions even the superficial invasion are stage Ib cancers.

    Invasion is limited to measured stromal invasion with maximum depth of 5.0 mm and no wider than 7.0 mm

    Stage Ia1

    Measured invasion of stroma no greater than 3.0 mm in depth and no wider than 7.0 mm.

    Stage Ia2

    Measured invasion of stroma greater than 3 mm and no greater than 5 mm and no wider than 7 mm.

    The depth of invasion should not be more than 5 mm taken from the base of the epithelium, surface or glandular, from which it originates. Vascular space involvement, venous or lymphatic, should not alter the staging.

    Stage Ib

    Clinical lesion confined to the cervix or preclinical lesion greater than stage Ia.

    Stage Ib1

    Clinical lesions no greaten than 4.0 cm in size

    Stage Ib2

    Clinical lesions greater than 4 cm in size

    Stage II

    Involvement of the vagina but not the lower third, or infiltration of the parametria but not out to the sidewall.

    Stage IIa

    Involvement of the vagina but no evidence of parametrial involvement

    Stage IIb

    Infiltration of the parametria but not out to the sidewall

    Stage III

    Involvement of the lower third of the vagina or extension to the pelvic sidewall; all cases with a hydronephrosis or nonfunctioning kidney should be included, unless they are know to be attributable to other cause

    Stage IIIa

    Involvement of the lower third of the vagina but not out to the pelvic sidewall if the parametria are involved

    Stage IIIb

    Extension onto the pelvic sidewall and/or hydronephrosis or nonfunctional kidney

    Stage IV

    Extension outside the reproductive tract

    Stage IVa

    Involvement of the mucosa of the bladder or rectum

    Stage IVb

    Distant metastasis or disease outside the true pelvis

    ¡@

  3. Treatment:

s Surgical Therapy:

¹ Stage Ia1: lesions with invasion less then 3 mm in depth (o )

j extrafascial hysterectomy without node dissection

k Therapeutic conization (for those patients desiring childbearing capability)

j extrafascial hysterectomy with pelvic node dissection, or

k modified radical hysterectomy with pelvic node dissection

¹ Stage Ia2: lesions with invasion between 3-5 mm in depth (o )

¡V Modified radical hysterectomy with pelvic node dissection

¹ Stage Ib/IIa:

¡V Radical hysterectomy, pelvic lymphadenectomy, and para-aortic lymph node evaluation

ø Types of Hysterectomy:

¡@

Type I

Extrafascial Hysterectomy

¡@

Type II

Modified Radical Hysterectomy

Medial 1/2 of the cardinal ligament

and uterosacral ligament

Type III

Radical Hysterectomy

Most of the cardinal ligaments

and uterosacral ligament

Upper 1/3 of the vagina

Type IV

Extended Radical Hysterectomy

Most of the cardinal ligaments

and uterosacral ligament

Up to 3/4 of the vagina

Periureteral tissue

Superior vesicle artery

Type V

Partial Exenteration

Most of the cardinal ligaments

and uterosacral ligament

Up to 3/4 of the vagina

Portions of the distal ureter and bladder

¡@

s Radiation Therapy:

¡@

Filename: Cervical Cancer

¡@