Induction

武功密笈

小黃藏書

OBS
GYN
Gyn Oncology
Infertility
Urogynecology

向上 Induction Induction of Labor Corticosteroid abruptio placentae Termination of Pregnancy at Term chlamydia amniotic fluid embolism Mumps Prolonged Preg

PGF2α (prostarmon f) (5mg/1ml vial)

I. Induction

PGF2A 3000 ug + D5W 500 cc: initial 3 ug/min (0.5 cc = 10 gtt), + 5 gtt q 15-30 min

proper dosage at 6-9 ug/min (20-30 gtt/min), max 24 ug/min (80 gtt/min)

end up of 3000 ug:

  1. bishop score imprved but not in labor, repeat one cycle
  2. bishop score > 8, repeat one cycle or change to oxytocin after 20-30min
  3. bishop score not improved, discontinue and repeat the same dosage next day

 

II. 2nd trimester termination of pregnancy

Extraovulary Foley traction

1. Preparation: 1000 ug + 3.8 ml NS (totally 4ml)

2. Foley catheter no 14-16F with baloon 20-30 ml

 

Interval (hr)

0

0.5

1-1.5

1-1.5

Q 1-1.5 hr

Infusion

250 ug

750 ug

1000 ug

1000 ug

1000 ug

 

3.5 ml NS

3.5 ml NS

3.5 ml NS

3.5 ml NS

3.5 ml NS

Note:

  1. no response after first infusion, reinsertion of Foley catheter
  2. traction of the Foley catheter to occlude the cervical OS
  3. testing dosage= 250 ug (1ml/1000ug in 3.8 ml NS) + NS 3.5 ml
  4. the thrid and subsequential dosages were given q one hour (average)
  5. strong response after testing dosage à reducing dosage to 500 ug (2ml) or prolonged interval of administration
  6. max 3000 ug, administration q one hour

 

III. prophylactic and therapeutic treament of PPH

  1. intravenous administration: same as part I.
  2. Intramyometrial direct injection: 1000 ug (0.2 cc)+ NS 3.8 cc

 

Prostarmone E (dinoprostone 0.5 mg) oral administration

  1. administration while OS > 1.5 cm
  2. interval q one hour, max 6 tablets
  3. discontinuation after 6 tablets and ineffective, repeat same regimen next day

 

Prostaglandin E2 (PGE2) prostin E2

For elective labor induction: one tab to be inserted high into the posterior fornix, the second tab may be insrted after 6-8 hrs if labor is not established, continuous administration of the drug for more than 2 days is not recommed, Max daily dosage 6 mg.

 

Pinton-S (10 units/1ml 1amp)

1amp in D5W or NS

  1. IV infusion
  2. Ordered and recorded in milliunits per minute
  3. Started at 1-2 milliunits per minute (1-2 gtt) to a maximum of 20 milliunits per minute (20 gtt)
  4. Cryatalloid solution

 

Misoprostol: 400-600μg vaginally 4 hrs before termination

< 6-7 wks:

Day 1 200 mg or 600 mg mifepristone

Day 3 400 pr 800 μg misoprostol

Abortion in 4 hours (repeated after 3 hrs if no expulsion occurs)